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Best Over-the-Counter Medicine for Flu — What Licensed Clinicians Recommend

Flu season in New York City can hit hard — crowded trains, packed offices, and unpredictable weather make it easy to catch and difficult to kick. When symptoms strike, knowing which over-the-counter (OTC) remedies actually help can make all the difference.

Here’s what Sickday’s licensed clinicians — including certified nurse practitioners and physician assistants — recommend when treating flu symptoms at home.


🤒 Common Flu Symptoms

Before you reach for medication, watch for these typical signs:

  • Fever and chills
  • Fatigue and body aches
  • Sore throat or persistent cough
  • Nasal congestion or runny nose
  • Headaches

Most cases don’t require prescription treatment — but managing your symptoms effectively can help you recover faster and more comfortably.


💊 Clinician-Recommended OTC Medications

1. Pain + Fever Relief

  • Acetaminophen (Tylenol) and Ibuprofen (Advil, Motrin) help reduce fever and ease body aches and headaches.

2. Cough Relief

  • Dextromethorphan (Robitussin, Delsym): For dry, hacking coughs
  • Guaifenesin (Mucinex): Loosens mucus and helps with productive coughing

3. Nasal and Sinus Congestion

  • Pseudoephedrine (Sudafed): For sinus pressure and congestion (available behind the pharmacy counter)
  • Saline sprays or short-term decongestant sprays can also help — use with care and only for a few days

4. Sore Throat Support

  • Lozenges, sprays with benzocaine, or warm salt water rinses

⚠️ Be mindful not to double-dose ingredients — many combination flu meds contain the same active ingredients (e.g., acetaminophen) across products.


🧠 Additional Clinician Tips

  • Stay hydrated with water, tea, and electrolyte drinks
  • Rest as much as possible — your immune system needs the downtime
  • Avoid alcohol or caffeine, which can dehydrate you
  • Use a humidifier to ease congestion and throat discomfort

🏠 When to Consider In-Home Care

Sickday provides same-day or next-day house calls across all five boroughs of NYC. If you’re:

  • Too sick to leave the house
  • Unsure whether it’s the flu or something else (like COVID or strep)
  • Needing a clinical exam, guidance, or flu testing
  • Looking to avoid urgent care lines and exposure

A licensed Sickday clinician can come directly to your home, assess your symptoms, and provide treatment recommendations — with no waiting room involved.


🚨 When to Seek Immediate Medical Attention

If you experience:

  • Trouble breathing
  • Chest pain
  • Persistent high fever
  • Symptoms lasting more than a week
  • Worsening fatigue or confusion

Contact your clinician or seek emergency care.


You don’t have to tough it out alone. Get the right care — right at home.
Book an in-home visit with a licensed Sickday clinician today.

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